Dr. Tuley teaches chemistry at Rose-Hulman where his special interests include general chemistry, organic chemistry, and biochemistry. His research interests include medicinal chemistry, genetic code expansion, and chemical biology. He earned his Ph.D. at Texas A&M. In his free time, he enjoys playing the guitar, fishing and spending time with his family.

Academic Degrees

Ph.D. Chemistry, Texas A&M University (Research advisor: Prof. Wenshe Liu), 2015

B.S. Chemistry, Texas A&M University-Corpus Christi, 2009

Awards & Honors

NIH-IRACDA Postdoctoral Fellowship, UT-Austin CORE program (Collaborative Opportunities for Research Educators) - 2015

NCI Research Supplement to Promote Diversity in Health-Related Research - 2013

John Chapman Endowed Scholarship 2006 Welch Undergraduate Research Fellowship - 2005-09

Publications & Presentations

Tuley, A.; Fast, W. “The Taxonomy of Covalent Inhibitors,” Biochemistry 2018, 57 (24), 3326-3337.

Burstein-Teitelbaum, G.; Er, J. A. V.; Monzingo, A. F.; Tuley, A.; Fast, W. “Dissection, Optimization, and Structural Analysis of a Covalent Irreversible DDAH1 Inhibitor,” Biochemistry 2018, 57 (30), pp 4574–4582.

Schardon, C.; Tuley, A.; Er, J.; Swartzel, J.; Fast, W. “Selective Covalent Protein Modification by 4-Halopyridines Through Catalysis,” ChemBioChem 2017, 18, 1-7.

Tuley, A.; Wang, Y.-S., Fang, Q.; Kurra, Y.; Rezenom, Y.; Liu, W. R. “The Genetic Incorporation of Thirteen Novel Non-Canonical Amino Acids,” Chem. Commun. 2014, 50, 2673-2675.

Tuley, A.; Lee, Y. J.; Wu, B.; Wang, Z. U.; Liu, W. R. “A Genetically Encoded Aldehyde for Rapid Protein Labelling,” Chem. Commun. 2014, 50, 7424-7426. Highlighted on the back cover of Chemical Communications.

Research Experiences

Medicinal Chemistry

Genetic Code Expansion

Chemical Biology

Teaching Interests

General Chemistry

Organic Chemistry


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