Week	Date	Time	DESCRIPTION OF LABORATORY EXPERIENCE
1	Dec 3	Wed 1-3pm	Course Orientation and Explanation of Syllabus Introduction to Web-based Course Structure and Online Communication Laboratory Safety Training and Lab Tour Passport Signatures Learning Style Profile Bacterial Culture
2	Dec 10	Wed 1-3pm	Biomedical Engineering and Biomedical Research Cellular Biology Research Methods Organ Bioengineering Passport Signatures Electromagnetic Radiation Therapy Research & Development Genetic Engineering and Microbiology: Bacterial Culture, Identification and Use in Biomedical Research
3	Dec 17	Wed 1-3pm	Introduction to Cell Culture Suspension Cell Culture Methods, Primary vs Transformed Cell Lines and Cell Counting
4	Jan 7	Wed 1-3pm	Passport Signatures Passport Signatures Cell Culture Methods, Continued Adherent cells and viability testing
5	Jan 14	Wed 1-3pm	Blood Testing Laboratory Laboratory Safety: Bloodborne Pathogens Patient – Doctor relationship Blood drawing, proper labeling Blood Typing Blood Smear Hematocrit Sedimentation Rate
6	Jan 21	Wed 1-3pm	Clinical Tests 1 Differential Cell Counting (comparison with automated counts) SPE Serum Protein Electrophoresis Dilution Series & Calculation of Titer Passport Signatures Serum Antibody Tests RID Radial Immuno-Diffusion Assay
7	Jan 28	Wed 1-3pm	Clinical Tests 2 Introduction to clinical tests and appropriate test controls Analytical errors Cost analysis ELISA (sandwich, direct assay) NBT Nitroblue Tetrazolium Test Cell Proliferation Tests (PHA) Latex Agglutination Test Complement Fixation Test Antibody/Antigen Precipitation Tests Flow Cytometry Analysis Passport Signatures Coombs Tests (direct and indirect) Virus Neutralization Test
8	Feb 4	Wed 1-3pm	Motor and Sensory Tests Motor Point Stimulation Nerve Conduction Velocity Muscle Contraction Tinel Test Point Discrimination Phalen’s Test Passport Signatures Strength Test Pain as indication of deregulated homeostasis Medical Diagnostic Imaging
9	Feb 11	Wed 1-3pm	Homeostasis pH (acid-base balance) Osmotic pressure (Osmometer) Temperature (temperature sensors) Blood pressure (Blood pressure cuffs) Passport Signatures Electrolytes (urinalysis dip strips, electrodes) Measurement units and conversion tables Respiratory Rates
10	Feb 18	Wed 1-3pm	Final Examination Evaluating the Student’s Understanding of Biomedical Research Clinical Methods

The course “Introduction to Biomedical Research: Clinical Methodology” is designed to introduce applied biology/bioengineering students to the basics of biomedical research using the clinical methodology typical of patient sample analysis. Students will experience the basics of cell culture, bacterial culture, protein, blood and urine analysis and will learn to perform venipuncture. Students will learn to relate testing procedures with specific diseases and to use data obtained from laboratory testing to understand more about specific patient health problems.