Section I

•Thermodynamics
•Water, pH, and Buffers
•Amino Acids
•Peptide Bond & Secondary Structure
•Classes of Proteins
•Protein Folding
•Introduction to Protein Structure Determination
•Carbohydrate Chemistry
•Nucleotides

Section II
•Introduction to Enzymes
•Enzyme Kinetics
•Examples of Enzyme Mechanisms
•Vitamins and Coenzymes
•Enzyme Regulation
•Enzyme Inhibition
•Kinetic Analysis of Inhibition

•Properties of Lipids
•Membrane Physiology
•Signal Transduction

Section III
•Introduction to Metabolism
•Bioenergetics
•Glycolysis
•Gluconeogenesis
•Glycogen Metabolism
•Hexose Monophosphate Shunt
•Regulation of Glucose Metabolism
•Pyruvate Dehydrogenase
•TCA Cycle
•Electron Transport&Oxidative Phosphorylation
•Shuttle Mechanisms

•Lipid Metabolism
•Ketone Bodies
•Introduction to Amino Acid Metabolism
•Amino Acid Breakdown
•Urea Cycle
•Nucleotide Metabolism

•Installing Dyknow
•Study guide for Exam 1

•Assignments Week 0 & 1
•Assignments Week 2
•Assignments Week 3
•Assignments Week 4
•Assignments Week 5
•Assignments Week 6
•Assignments Week 7
•Assignments Week 8
•Assignments Week 9
•Assignments Week 10 (new)

•Syllabus

•Functional Groups
•Water Properties Handout
•pH and Buffers Tutorial
•Amino Acid Structures
•Amino Acids Handout
•Peptide Introduction Handout
•Helical Wheel and Net
•Protein Representations & Folding Handout
•Carbohydrate Chemistry Handout
•Nucleotides & Nucleic Acids Handout

•Enzyme Introduction Handout
•Mathematical Modeling and Kinetics
•Enzyme Mechanisms Handout
•Enzyme Kinetics Handout
•Vitamins Handout
•Mathematical Modeling and Kinetics

•Vitamins Handout
•Enzyme Regulation and Inhibition Handout
•Lipids & Membranes Handout
•Signal Transduction Handout

•Introduction to Metabolism Handout
•Glycolysis Handout
•Pyruvate Oxidation Handout
•Electron Transport Handout
•Glucose Metabolism Handout
•Metabolic Regulation Handout
•Starvation and Diabetes Handout

•Metabolic Pathways
•Reaction Examples

•Endocrine Notes

•Alpha helix
•Anti-parallel beta
•Parallel beta
•Large beta sheet

•Titration spreadsheet
•pI calculator spreadsheet
•Enzyme kinetics simulation spreadsheet
•Non-linear regression for Michaelis-Menten enzyme

•Problem Set 1
      •Answers
•Problem Set 2
      •Answers
•Problem Set 3
      •Answers
•Problem Set 4
      •Answers
•Problem Set 5
      •Answers
•Problem Set 6
     •Answers
•Problem Set 7
     •Answers
•Problem Set 8
     •Answers

•Discussion Problem
     •Enzyme A Active Site

•Exam 2
•Exam 2 data spreadsheet
•Exam 3
•Exam 3 data spreadsheet (typos corrected)