We propose a model to describe the interaction between a diseased fish population and their predators. Analysis of the system is performed to determine the stability of equilibrium points for a large range of parameter values. The existence and uniqueness of solutions is established and solutions are shown to be uniformly bounded for all nonnegative initial conditions. The model predicts that a deadly disease and a predator population cannot co-exist. Numerical simulations illustrate a variety of dynamical behaviors that can be obtained by varying the problem data.