Professors Allison, Brandt, R. DeVasher, Erwin, Hoffman, Morris, Mottel, Mueller, Tilstra, Weatherman and Wilson.

CHEM 111 General Chemistry I   3R-3L-3C  F,W,S  Prereq: None; Coreq: CHEM111L
Topics include stoichiometry, nomenclature, phases, and writing balanced chemical equations. Quantum theory is introduced in relation to chemical applications. Atomic structure is introduced. Bonding principles and molecular structure are discussed in terms of Lewis Dot Structures, Valence Bond Theory, VSEPR Theory, Hybridization, and Molecular Orbital Theory.

CHEM 111L General Chemistry I Laboratory   0R-3L-1C  F,W,S  Prereq: None; Coreq: CHEM 111
Fundamental chemistry laboratory skills are introduced along with data analysis in support of topics presented in CHEM111 recitation.

CHEM 112 Chemistry Honors  4R-3L-5C  F  Prereq: Advanced placement
An accelerated course covering topics in CHEM 111 and CHEM 113. Upon successful completion of this course, an additional 3 credits will be awarded. Enrollment is limited to those students who complete the Rose-Hulman online Chemistry Advanced Placement Examination given prior to the freshman orientation period.

CHEM 113 General Chemistry II  3R-3L-3C  W,S  Prereq: CHEM 111 and CHEM 111L;  Coreq: CHEM 113L
Topics in this course include the fundamentals of thermodynamics and kinetics. The fundamentals of chemical equilibrium are introduced. Definitions of acid and bases are discussed utilizing the Bronsted-Lowry and Lewis models. Nuclear chemistry is also included.

CHEM 113L General Chemistry II Laboratory   0R-3L-1C  W,S  Prereq: CHEM 111 and CHEM 111L; Coreq: CHEM 113
Fundamental chemistry laboratory skills are introduced along with data analysis in support of topics presented in CHEM113 recitation.

CHEM 115 General Chemistry III  3R-3L-3C  W,S  Prereq: CHEM 113 and CHEM 113L, or CHEM 112; Coreq: CHEM 115L
Topics in this course include acid-base reactions, electrochemistry, and coordination chemistry.

CHEM 115L General Chemistry III Laboratory  0R-3L-1C  W,S  Prereq: CHEM 113 and CHEM 113L or CHEM 112; Coreq: CHEM 115
Fundamental chemistry laboratory skills are introduced along with data analysis in support of topics presented in CHEM113 recitation.

CHEM 200 Career Preparation  1R-0L-1C  W
This course is for chemistry and biochemistry majors to be taken in the second year. The course addresses career choices, summer opportunities, employment and graduate school preparation, and curriculum vitae and resumes preparation. Cross-listed with MA200, and SV200.

CHEM 225 Analytical Chemistry  3R-3L-3C  F, S  Prereq: CHEM 115 and CHEM 115L;  Coreq: CHEM 225L
This laboratory-driven course is an introduction to classical and modern quantitative analysis with emphasis on calculations, separations, and precise and accurate measurements. Theoretical and practical perspectives of chemical analysis are considered. Chemical instrumentation includes recording pH/mV meters, constant rate burets, colorimeters, spectrophotometers, high performance liquid chromatographs and gas-liquid chromatographs.

CHEM 225L Analytical Chemistry Laboratory  0R-3L-1C  F, S  Prereq: CHEM 115 and CHEM 115L;  Coreq: CHEM 225
This course represents the laboratory component of analytical chemistry.  Practicums are part of the grade along with reports.

CHEM 251 Organic Chemistry I  3R-0L-3C  F  Pre: CHEM 113 and CHEM 113L, or CHEM 112;  Coreq: CHEM 251L
An introduction to the classification of organic compounds, their structural features, including stereochemistry, and concepts related to reaction mechanisms and synthetic methods.

CHEM 251L Organic Chemistry I Laboratory  0R-3L-1C  F  Prereq: CHEM 113 and CHEM 113L, or CHEM 112;  Coreq: CHEM 251
Organic Laboratory techniques are developed along with appropriate spectroscopic methods. Assessment is in part via practicums. Computational chemistry methods and green chemistry approaches are also introduced.

CHEM 252 Organic Chemistry II  3R-0L-3C  W  Prereq: CHEM 251 and CHEM 251L;  Coreq: CHEM 252L
Continuation of Organic Chemistry I with greater emphasis on reaction mechanisms and synthesis, and an introduction to the methods used to determine structure, including IR and NMR spectroscopy and mass spectrometry.

CHEM 252L Organic Chemistry II Laboratory  0R-3L-1C  W  Prereq: CHEM 251 and CHEM 251L;  Coreq: CHEM 252
A continuation of CHEM251L where additional, more complicated synthetic techniques and methods along with additional spectroscopic techniques are introduced. Assessment is in part via practicums.

CHEM 253 Organic Chemistry III   3R-0L-3C  S  Prereq: CHEM 252 and CHEM 252L;  Coreq: CHEM 253L
Study of carbanions, classical and non-classical carbocations, polyfunctional compounds, heterocyclics, orbital symmetry and more advanced reaction mechanisms, molecular rearrangements and syntheses.

CHEM 253L Organic Chemistry III Laboratory   0R-4L-1C  S  Prereq: CHEM 252 and CHEM 252L;  Coreq: CHEM 253
Project based laboratory where techniques and skills developed in the previous organic laboratories are applied to more open-ended problems.

CHEM 264 Introduction to Environmental Science   4R-0L-4C  W  Prereq: CHEM 113 and CHEM 113L
This course will introduce students to the broad field of environmental science by examining the biological, chemical, and physical processes that regulate the earth’s ecosystems and the effect that anthropogenic activity has in disrupting these components on the local and global scale. A final aspect of the course will discuss sustainable human utilization of natural resources. Cross-listed with BIO264.

CHEM 275 Special Topics in Chemistry   (1-4)R-0L-(1-4)C  Prereq: Permission of instructor
Studies in topics of current chemical interest not addressed in other named courses.

CHEM 276 Directed Laboratory Study in Chemistry   0R-3L-1C  F  Prereq: Consent of instructor
Laboratory studies designed to supplement the background of entering students with an exceptional high school background in chemistry. This course is recommended for students entering with an AP 5 score.

CHEM 290 Chemical Research   0R-(4-8)L-(1-2)C
Research performed under the direction of a faculty member selected by mutual agreement. This course is designed for research performed before taking CHEM291. Students may register for 1 to 2 credit hours per quarter.

CHEM 291 Introduction to Chemical Research  2R-4L-3C  W  Prereq: CHEM 113/113L, or 112
Students will be introduced to skills necessary for conducting chemical research. Students will gain proficiency in: (1) literature searching of primary, secondary, and tertiary sources emphasizing the use of online databases; (2) laboratory skills involving synthesis, characterization, analysis, and keeping a notebook; (3) safety practice including MSDS interpretation; and (4) ethical conduct in collecting and reporting data and results. Students will also discuss research projects with at least three faculty members and be required to attend all seminars during the quarter.

CHEM 304 Glassblowing   1R-3L-1C  S  Prereq: Chemistry majors only or consent of instructor
A laboratory course in the manufacture, use and repair of scientific glassware. Six types of seals are constructed; a student-designed project is required.

CHEM 326 Bioanalytical Chemistry   3R-4L-4-C F Prereq: CHEM 225 and CHEM 225L
Addresses instrumental methods of analysis applicable to biochemistry including instrument design, operating principles, theory and application. Topics include molecular spectroscopic techniques in the infrared, visible and ultraviolet regions, including luminescence and Raman spectroscopy. Separation techniques including liquid chromatography and capillary electrophoresis are also addressed.

CHEM 327 Advanced Analytical Chemistry   3R-4L-4C  W  Prereq: CHEM 225 and CHEM 225L
Addresses theory, operating principles, and application of instrumental methods for chemical analysis in the areas of atomic spectroscopy, x-ray techniques, gas chromatography and electroanalytical methods.

CHEM 330 Biochemistry I   4R-0L-4C  F  Prereq: CHEM 252
Includes the structure and function of biological molecules, enzyme kinetics and mechanisms, and the reactions, strategy, and regulation of carbohydrate metabolism.

CHEM 331 Biochemistry II   4R-0L-4C  W  Prereq: CHEM 330 and BIO 210
Includes the reactions, strategy, and regulation of the major metabolic pathways in humans and of selected pathways in plants, and the storage, repair, and transmission of genetic information.

CHEM 360 Introduction to Physical Chemistry for Engineers   3.5R-2L-4C W, S  Prereq: CHE 303, CHE 304, and CHEM 115
Introduction to statistical thermodynamics, electrochemistry, chemical kinetics, surface chemistry and colloid science. The laboratory will meet for 4 hours alternate weeks and will investigate topics associated with chemical kinetics and surface phenomena.

CHEM 361 Physical Chemistry I   4R-2L-4C  F  Prereq: CHEM 115, CHEM 115L, MA212 and MA 381
Covers the laws of thermodynamics, free energy, gases, phase equilibria and solutions. Emphasizes the applications of differential and integral calculus and includes an introduction to statistical thermodynamics and surface chemistry. The laboratory will meet for 4 hours on alternate weeks and will investigate topics associated with thermodynamics and phase equilibrium.

CHEM 362 Physical Chemistry II   3R-2L-4C  W  Pre: CHEM 361
Covers chemical equilibria, statistical mechanics, kinetics and electrochemistry. The laboratory will meet for 4 hours on alternate weeks.

CHEM 363 Quantum Chemistry & Molecular Spectroscopy   4R-0L-4C  S  Prereq: CHEM 111, CHEM 111L, MA 212, PH 112
Covers elementary quantum mechanics with emphasis on applications in molecular structure.

CHEM 371 Environmental Analytical Chemistry   3R-4L-4C  F  Prereq: CHEM 251 and CHEM 251L (or concurrent enrollment), and CHEM 225 and CHEM 225L and CHEM 264
This course is a laboratory-driven course where processes involved in performing environmentalanalytical chemistry are addressed. The focus of this course is on the chemical principles,analytical theory, instrumentation, and methods employed to quantitatively and qualitatively analyze pollutants in soil, water, biological tissues, and the atmosphere. Several techniques will be included in the course: sampling (obtaining a representative sample of complex system);sample preparation (extraction, clean-up, pre-concentration, derivitization, digestion, etc.); data acquisition (The laboratory will include use of EPA/ASTM methods/protocols, method development, etc.); and data handling and analysis (statistics, signals, noise, etc.).

CHEM 391 Research Proposal  1R-0L-1C  F,W,S  Prereq: CHEM 291, RH 330;  Coreq: CHEM 490
Students will take online lessons related to the generation and communication of research ideas culminating in the production of a research proposal. The research proposal will be written under the direction of a faculty member of record for the student’s CHEM490 or by other faculty member selected by mutual agreement.

CHEM 395 Chemistry Seminar  0R-0L-0C  F  Prereq: None
Students will be required to attend and/or present research seminars, the number to be determined by the department. The students will register for the course in the fall of the third year and if all the requirements are met, the students will receive a grade of Satisfactory. Failure to meet the requirements during the fall quarter will result in No Grade and the student must complete the requirements by the end of the third year. If the requirements are not completed by the end of the third year, a grade of Unsatisfactory is assigned and must be rectified to meet graduation requirements.

CHEM 400 Chemical Communication I   1R-0L-1C  W  Prereq: CHEM 291
Students will engage in both oral and written communication that will culminate in a professional seminar and a published thesis at the completion of this course sequence. The emphasis of this course is to provide instruction in written communication. The fundamental skills useful for composition of professional chemistry communications is introduced culminating in a research prospectus. Students will also recognize elements of effective oral presentations by attending and evaluating seminar speakers in the chemistry department’s seminar series.

CHEM 401 Chemical Communication II   1R-0L-1C  F  Prereq: CHEM 400 and CHEM 490
Students will engage in both oral and written communication that will culminate in a professional seminar and a published thesis at the completion of this course sequence. Students will learn methods associated with constructing results and analysis sections of formal research reports consistent with the guidelines presented in The ACS Style Manual. Students will also recognize elements of effective oral presentations by attending and evaluating seminar speakers in the chemistry department’s seminar series.

CHEM 402 Chemical Communication III   1R-0L-1C  W  Prereq: CHEM 401
The emphasis of this course is to provide instruction in oral communication. Students will be taught fundamental skills useful for public presentation of research and its results. Students  will also be required to attend the chemistry department’s seminar series.

CHEM 403 Chemical Communication IV   1R-0L-1C  S  Prereq: CHEM 402
Students will publish a thesis and deliver a professional seminar on their undergraduate research.

CHEM 430 Advanced Biochemistry   4R-0L-4C  S  Prereq: CHEM 330
An in-depth exploration of selected topics from the current biochemistry scientific literature, including molecular mechanisms of infectious diseases and genetic disorders, methods for rational drug design, and relationships between structure and function for biological molecules.

CHEM 433 Biochemistry Laboratory   0R-3L-lC  S  Prereq: CHEM 330
Fundamental techniques employed in isolation, characterization and study of biomolecules, and enzyme kinetics. Techniques used may include homogenization, solvent extraction, centrifugation, salt fractionation, chromatography, and electrophoresis.

CHEM 441 Inorganic Chemistry I    4R-0L-4C  F  Prereq: CHEM252 and CHEM 362 or CHEM 360
The chemistry of non-metals. This course consists of a systematic study of the properties and reactions of the elements and their compounds based upon modern theories of the chemical bond, as well as from the viewpoint of atomic structure and the periodic law.

CHEM 442 Inorganic Chemistry II   3R-4L-4C  W  Prereq: CHEM 441
The chemistry of metals. Modern theories such as valence bond, molecular orbital, electrostatic and ligand field are used to explain the properties of complex ions. Synthesis and characterization of complexes are done in the lab.

CHEM 451 Organic Structure Determination   2R-8L-4C  S  Prereq: CHEM 253 or permission of instructor
Chemical and spectroscopic identification of organic compounds. Study of nuclear magnetic resonance and mass spectrometry, infrared spectroscopy and other techniques applied to structure elucidation and stereochemistry.

CHEM 465 Environmental Organic Chemistry  4R-0L-4C  Prereq: CHEM 251 or CE 564 or consent of instructor
This course will examine the processes that control the fate of organic contaminants in the environment. Course topics include applying chemical thermodynamics to understand environmental fate, aqueous solubilities, partitioning behavior into various environmental compartments, sorption behavior, and the mechanisms and kinetics of some important abiotic transformations.

CHEM 470 Special Topics in Chemistry   (1-4)R-0L-(1-4)C  F,W,S  Prereq: permission of instructor
Studies in advanced topics of current chemical interest not addressed in other named courses.

CHEM 476 Directed Laboratory Study in Chemistry   0R-4L-1C  F,W,S  Prereq: To be taken concurrently with the appropriate elective not accompanied by an identified laboratory component.
Laboratory studies designed to supplement an area concentration in organic, inorganic, analytical, physical, or some other field of chemistry.

CHEM 477 Directed Study in Chemistry  (1-4)R-0L-(1-4)C  F,W,S  Prereq: Permission of instructor
Allows individual study in a topic not usually offered. A student may take 1 to 4 credits. A maximum of 4 credits is permitted.

CHEM 490 Chemical Research  0R-(4-12)L-(1-3)C  Prereq: CHEM 291
Research performed under the direction of a faculty member selected by mutual agreement. Students may register for 1 to 3 credit hours per quarter.

CHEM 491 Research Thesis  1R-0L-1C  F,W,S  Prereq: CHEM 490
Students will publish a thesis on their undergraduate research. The thesis will be written under the direction of a faculty member of record for the student’s CHEM490 or by other faculty member selected by mutual agreement.

CHEM 495  Chemistry Seminar  0R-0L-0C  F  Prereq: None
Students will be required to attend research seminars. If the requirement is not completed by the end of the quarter, a grade of Unsatisfactory is assigned and must be rectified to meet graduation requirements.

CHEM 496  Chemistry Seminar  0R-0L-0C  W  Prereq: None
Students will be required to attend research seminars. If the requirement is not completed by the end of the quarter, a grade of Unsatisfactory is assigned and must be rectified to meet graduation requirements.

CHEM 497 Research Presentation 1R-0L-1C F W S Prereq: CHEM 490
Students will deliver a professional seminar on their undergraduate research. A student must have at least three credit hours of CHEM490. The seminar will be prepared under the direction of a faculty member of record for the student’s CHEM490 or by other faculty member selected by mutual agreement.

CHEM 530 Advanced Biochemistry 4R-0L-4C S Prereq: CHEM 330
An in-depth exploration of selected topics from the current biochemistry scientific literature, including molecular mechanisms of infectious diseases and genetic disorders, methods for rational drug design, and relationships between structure and function for biological molecules. Students enrolled in CHEM 530 must complete a project not covered in CHEM 430. A student may not receive credit for both CHEM 430 and CHEM 530.

CHEM 531 Biochemical Instrumentation   3R-4L-4C  Prereq: BIO 210 and CHEM 330
This project-based course includes approaches for the analysis of biochemical experimental problems, experimental design for molecular biology and biochemistry, and the theoretical basis and practical aspects of operating instruments used in biochemical research.

CHEM 532 Biochemical Pharmacology 4R-0L-4C  Prereq: CHEM 330
Topics include medicinal chemistry and molecular pharmacology. The topics will also include a survey of potential drug targets, the molecular interactions between drugs and their targets, the drug discovery and development process and case studies of drugs treating diseases such as cancer, bacterial and viral infection, and neurological disorders.

CHEM 545 Organometallic Chemistry   4R-0L-4C   Prereq: CHEM 115, CHEM 252
A survey of the chemistry of main group organometallic compounds and organo-transition metal complexes. Reaction mechanisms and uses in organic synthesis and catalysis are studied.

CHEM 552 Synthetic Organic Chemistry   4R-0L-4C  Prereq: CHEM 253
A survey of contemporary methodology in organic synthesis. Retrosynthetic analysis, functional group transformations, condensation chemistry, and organometallic reagents will be stressed. Includes computer assisted synthesis.

CHEM 554 Theoretical Organic Chemistry   4R-0L-4C  Prereq: CHEM 253 and CHEM 361 or CHEM 360 or permission of instructor
Study of physical and chemical methods used to investigate organic reaction mechanisms; the chemistry of carbenes; organic photochemistry.

CHEM 555 Natural Products  4R-0L-4C  Prereq: CHEM 253 or permission of instructor
A study of naturally occurring materials such as carbohydrates, lipids, amino acids, terpenes and steroids. The course also entails a discussion of synthesis, biosynthesis, structure elucidation, selected degradation and other reactions as well as some medicinal characteristics of selected natural products.

CHEM 557 Synthetic Polymer Chemistry  4R-0L-4C  Prereq: CHEM 252
Polymer synthesis, reactions, and applications. Organic chemistry of polymer synthesis and modification. Design of polymer systems that meet certain performance criteria or have desirable physical properties.

CHEM 561 Advanced Physical Chemistry  4R-0L-4C  Prereq: CHEM 363
Addresses a variety of topics in quantum mechanics, statistical thermodynamics or kinetics.

CHEM 562 Physical Polymer Chemistry  4R-0L-4C  Prereq: CHEM 361 or CHE 303
Physical behavior of polymers. Physical properties, molecular weight determination, relationship between morphology and mechanical properties.

CHEM 570 Special Topics in Chemistry  (1-4)R-0L-(1-4)C  F,W,S  Prereq: permission of instructor
Studies in advanced topics of current chemical interest not addressed in other named courses. If cross-listed with CHEM470, students in CHEM570 will need to complete an additional project.

CHEM 599 Thesis Research F, W, S
Graduate students only. Credits as assigned; however, not more than 12 credits will be applied toward the requirements of the M.S. degree.